Endocrine Abstracts

Hepatocytes are both insulin sensitive and the primary site for synthesis of SHBG. Thus, it is possible that a condition of hepatic insulin resistance may impair hepatic synthesis of SHBG. In this study, we assessed SHBG circulating levels after 30 days of a very low-calorie ketogenic diet (VLCKD) based on high-biological value protein preparations diet (ISOMED) and natural food in a cohort of insulin-resistant obese male subjects. Moreover, we investigated the effects of expo...